Accutane is an effective and safe isotretinoin drug for the treatment of acne.
Accutane (isotretinoin) is the active form of vitamin A, which has a powerful effect regulating sebum. The emergence of this component almost led to a revolution in the treatment of severe acne. In fact, isotretinoin-based cosmetics are often a real lifesaver for those for whom other acne treatments have failed. At the same time, isotretinoin must be used with extreme caution, preferably under the supervision of a dermatologist, but it is indispensable for a number of reasons.
Isotretinoin (Generic Accutane)
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Learn the basic precautions for using Accutane from this article. You will be able to understand why this medicine is not immediately recommended for treatment. You should not think that this medication can be equally beneficial for everyone. You need to think a little more carefully before you start using this medication.
Before you start using Accutane for treatment, it is advisable to check your overall health. If you find that you have a health problem, your dermatologist may not recommend this medication or this medication may be recommended in smaller amounts.
Acne is one of the ten most common diseases. Approximately 20% of people suffering from acne, especially adolescents, have a severe form of the disease. Isotretinoin is the drug of choice for treating patients with these forms of the disease.
Isotretinoin is a monoaromatic retinoid. It was approved for acne treatment for the first time by FDA in 1982. Generics of isotretinoin began to appear since 2001.
Since that time a lot of experience has been accumulated in isotretinoin treatment of acne. Its high efficacy in patients with severe forms of the disease has been proved.
The basis of the high effectiveness of the drug is its influence on the main links in the pathogenesis of acne - sebum hyperproduction. The main target for the drug is sebocytes. Studies showed that isotretinoin administration for 6 weeks reduced sebum production by almost 90%.
Although the mechanisms of these effects remain unclear, the fact that they last for at least 6 months after treatment ends and provide a prolonged clinical effect of the drug seems important.
Who is Accutane (isotretinoin) prescribed to?
Accutane is highly effective in treating severe nodular acne, but this drug is not prescribed immediately to treat this problem. Even if a person has a mild form of acne, it is still not good and can make a person sad. Serious acne really should be treated as soon as possible, as it is not just a physical problem. A person with a severe form of acne does not feel confident in everyday life. The person has a lot of problems to communicate freely with other people, to establish close relationships, to advance in the workplace, etc. Therefore, this problem can become the most important one in a person's life.
The anti-acne drug Accutane has been shown to prevent the development of skin cancer. The treatment reduced the development of skin cancer by an average of 63 percent. Scientists believe this treatment is only justified for people with genetic defects that contribute to cancer. This particular drug would not be widely used for cancer prevention because long-term use can cause serious side effects, including liver abnormalities and high blood fat levels. Accutane also causes birth defects in pregnant women.
Who is contraindicated for Accutane (isotretinoin)?
The very first thing you should remember about using Accutane (isotretinoin) is that this drug is contraindicated for pregnant women. A pregnancy test is recommended before you start using Accutane for treatment. Accutane may not work for some people for a variety of reasons. This medication can make you allergic, in which case you should not use Accutane to treat it, no matter how badly you want to get rid of a serious acne problem.
Despite significant advances in acne therapy, the problem of improving its treatment is very relevant. Currently, retinoids are the drugs of first choice. Considering that the side effects of systemic isotretinoin are dose-dependent, it is very important to search for methods that can reduce the daily and course dose of the drug and increase the compliance of acne patients with therapy.